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Shisa2tm1Sia
Targeted Allele Detail
Nomenclature
Symbol: Shisa2tm1Sia
Name: shisa family member 2; targeted mutation 1, Shinichi Aizawa
MGI ID: MGI:3715222
Synonyms: mShisalacZ
Gene: Shisa2  Location: Chr14:59625308-59631660 bp, + strand  Genetic Position: Chr14, 31.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122557
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 and the following intron were replaced with a lacZ/neo cassette creating a null allele. Insertion was confirmed by RT-PCR analysis and a beta-galactosidase assay. (J:122557)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 32 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shisa2 Mutation:  8 strains or lines available
References
Original:  J:122557 Furushima K, et al., Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings. Dev Biol. 2007 Jun 15;306(2):480-92
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory