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Hand2tm1Cse
Targeted Allele Detail
Nomenclature
Symbol: Hand2tm1Cse
Name: heart and neural crest derivatives expressed transcript 2; targeted mutation 1, Peter Cserjesi
MGI ID: MGI:3715149
Synonyms: Hand22F, Hand2loxP
Gene: Hand2  Location: Chr8:57320983-57324517 bp, + strand  Genetic Position: Chr8, 29.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122604
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted to flank the exon. A frt-flanked neo was included upstream of the 3' loxP site. Frt-mediated recombination removed the neo, leaving the single exon floxed. (J:122604)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hand2 Mutation:  0 strains or lines available
References
Original:  J:122604 Morikawa Y, et al., Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system. Dev Biol. 2007 Jul 1;307(1):114-26
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory