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Map2k1tm1.1Chrn
Targeted Allele Detail
Nomenclature
Symbol: Map2k1tm1.1Chrn
Name: mitogen-activated protein kinase kinase 1; targeted mutation 1.1, Jean Charron
MGI ID: MGI:3714919
Synonyms: Map2k1delta
Gene: Map2k1  Location: Chr9:64185770-64253631 bp, - strand  Genetic Position: Chr9, 34.55 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112223
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 3 is removed by Cre-mediated recombination to create a null allele. The absence of protein product was confirmed by western blot analysis. (J:112223)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Map2k1 Mutation:  79 strains or lines available
References
Original:  J:112223 Bissonauth V, et al., Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis. Development. 2006 Sep;133(17):3429-40
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory