Ldb1^tm1Witz
Targeted Allele Detail

Summary

• Symbol: Ldb1^tm1Witz
• Name: LIM domain binding 1; targeted mutation 1, Ralph Witzgall
• MGI ID: MGI:3714803
• Gene: Ldb1 Location: Chr19:46020009-46033653 bp, - strand Genetic Position: Chr19, 38.75 cM
• Alliance: Ldb1^tm1Witz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122505
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exons 1-9. (J:122505)

Disease models

Expression

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ldb1 Mutation: 34 strains or lines available

References

• Original: J:122505 Suleiman H, et al., The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes. Dev Biol. 2007 Apr 15;304(2):701-12
• All: 4 reference(s)