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Ebf2tm2.1(Zfp423)Reed
Targeted Allele Detail
Summary
Symbol: Ebf2tm2.1(Zfp423)Reed
Name: early B cell factor 2; targeted mutation 2.1, Randall R Reed
MGI ID: MGI:3714342
Synonyms: O/E3OAZ
Gene: Ebf2  Location: Chr14:67470741-67668367 bp, + strand  Genetic Position: Chr14, 34.63 cM, cytoband D-E1
Alliance: Ebf2tm2.1(Zfp423)Reed page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122275
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsThe floxed neo was removed from the locus via cre mediated recombination, leaving the full length cDNA for zing finger protein 423, followed by IRES-3NLS-YFP-pA in place of the first five exons of the locus. (J:122275)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf2 Mutation:  30 strains or lines available
References
Original:  J:122275 Cheng LE, et al., Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis. Neuron. 2007 May 24;54(4):547-57
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory