Rela^tm1Rsch
Targeted Allele Detail

Summary

• Symbol: Rela^tm1Rsch
• Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian); targeted mutation 1, Roland Schmid
• MGI ID: MGI:3713697
• Synonyms: p65^flox, Rela^f, rela^floxed
• Gene: Rela Location: Chr19:5687511-5698158 bp, + strand Genetic Position: Chr19, 4.34 cM, cytoband B1-3
• Alliance: Rela^tm1Rsch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122194
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted between exons 6 and 7 and 5' of exon 10. (J:122194)

Expression

In Mice Carrying this Mutation:	4 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rela Mutation: 24 strains or lines available

References

• Original: J:122194 Algul H, et al., Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis. J Clin Invest. 2007 Jun;117(6):1490-501
• All: 58 reference(s)