Foxa2^{tm1.1(rtTa)Moon}
Targeted Allele Detail

Summary

• Symbol: Foxa2^{tm1.1(rtTa)Moon}
• Name: forkhead box A2; targeted mutation 1.1, Anne M Moon
• MGI ID: MGI:3713127
• Synonyms: Foxa2^ITA
• Gene: Foxa2 Location: Chr2:147884797-147888889 bp, - strand Genetic Position: Chr2, 73.38 cM
• Alliance: Foxa2^{tm1.1(rtTa)Moon} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119721
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: The high affinity variant of the reverse tetracycline controlled transactivator, together with an IRES, was inserted into the 3' UTR of the locus. The frt-flanked neo that was included in the vector downstream of the rtTa was removed by Flp recombinase expression. (J:119721)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxa2 Mutation: 26 strains or lines available

References

• Original: J:119721 Frank DU, et al., System for inducible expression of cre-recombinase from the Foxa2 locus in endoderm, notochord, and floor plate. Dev Dyn. 2007 Feb 15;236(4):1085-1092
• All: 1 reference(s)