Tcrb^tm3.1Che
Targeted Allele Detail

Summary

• Symbol: Tcrb^tm3.1Che
• Name: T cell receptor beta chain; targeted mutation 3.1, Jianzhu Chen
• MGI ID: MGI:3712149
• Synonyms: Vbeta(deltaneo)
• Gene: Tcrb Location: Chr6:40868230-41535305 bp, + strand Genetic Position: Chr6, cytoband A-C

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120387
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: The floxed pgk-neo was removed from the locus, leaving the Vbeta13 gene segment with its endogenous promoter and recombination signal sequences upstream of the D segment. (J:120387)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcrb Mutation: 94 strains or lines available

References

• Original: J:120387 Sieh P, et al., Distinct control of the frequency and allelic exclusion of the V beta gene rearrangement at the TCR beta locus. J Immunol. 2001 Aug 15;167(4):2121-9
• All: 1 reference(s)