Tg(Pax6-cre)1Zkoz
Transgene Detail
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Symbol: |
Tg(Pax6-cre)1Zkoz |
Name: |
transgene insertion 1, Zbynek Kozmik |
MGI ID: |
MGI:3711997 |
Synonyms: |
LR-cre |
Transgene: |
Tg(Pax6-cre)1Zkoz Location: unknown
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Alliance: |
Tg(Pax6-cre)1Zkoz page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Pax6-cre)1Zkoz expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Pax6 |
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Mutation details: Three copies of a lens-specific element derived from Pax6 were cloned upstream of the Pax6 P0 minimal promoter. The regulatory element is known to drive expression in the presumptive lens ectoderm as well as the surrounding head ectoderm. The ectoderm enhancer and promoter fragments were used to drive expression of cre recombinase and EGFP, connected through an IRES. Mice were maintained on an FVB/N background.
(J:121794)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pax6
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:121794 Kreslova J, et al., Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function. Genesis. 2007 Apr;45(4):157-68 |
All: |
2 reference(s) |
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