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Ddah1tm1Pval
Targeted Allele Detail
Nomenclature
Symbol: Ddah1tm1Pval
Name: dimethylarginine dimethylaminohydrolase 1; targeted mutation 1, Patrick Vallance
MGI ID: MGI:3711768
Synonyms: Ddah1-, Ddah1del
Gene: Ddah1  Location: Chr3:145758675-145894277 bp, + strand  Genetic Position: Chr3, 70.63 cM, cytoband H3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121719
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1, containing the initiation methionine and the first 100 amino acids, was replaced with a neomycin resistance cassette. (J:121719)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddah1 Mutation:  16 strains or lines available
References
Original:  J:121719 Leiper J, et al., Disruption of methylarginine metabolism impairs vascular homeostasis. Nat Med. 2007 Feb;13(2):198-203
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory