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Tmem158tm1Srn
Targeted Allele Detail
Nomenclature
Symbol: Tmem158tm1Srn
Name: transmembrane protein 158; targeted mutation 1, Manuel Serrano
MGI ID: MGI:3711170
Synonyms: Ris1-
Gene: Tmem158  Location: Chr9:123259058-123260789 bp, - strand  Genetic Position: Chr9, 73.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121067
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace the ORF with a neo cassette. RT-PCR confirmed absence of transcript in brain, spleen and kindney samples from mutants. (J:121067)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem158 Mutation:  2 strains or lines available
References
Original:  J:121067 Nieto M, et al., Normal cellular senescence and cancer susceptibility in mice genetically deficient in Ras-induced senescence-1 (Ris1). Oncogene. 2007 Mar 15;26(12):1673-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory