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Foxp1tm1Rao
Targeted Allele Detail
Nomenclature
Symbol: Foxp1tm1Rao
Name: forkhead box P1; targeted mutation 1, Anjana Rao
MGI ID: MGI:3711150
Synonyms: Foxp-
Gene: Foxp1  Location: Chr6:98925338-99522721 bp, - strand  Genetic Position: Chr6, 45.74 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112644
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ-neo was inserted to replace the sequence encoding the N-terminal two thirds of the protein, including the entire forkhead domain. The construct also removed the first translation start site to ensure efficient translation from the lacZ start codon. (J:112644)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxp1 Mutation:  45 strains or lines available
References
Original:  J:112644 Hu H, et al., Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 2006 Aug;7(8):819-26
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory