Del(12Bdkrb2-Bdkrb1)1Mki
Targeted Allele Detail
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Symbol: |
Del(12Bdkrb2-Bdkrb1)1Mki |
Name: |
deletion, Chr 12, Masao Kakoki 1 |
MGI ID: |
MGI:3710158 |
Synonyms: |
B1RB2R-null, Bdkrb1-/Bdkrb2-, Bdkrb2/Bdkrb1tm1Mki |
Gene: |
Del(12Bdkrb2-Bdkrb1)1Mki Location: unknown Genetic Position: Chr12, Syntenic
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Histological changes in the postischemic kidneys of wild type, Bdkrb2tm1Jfh/Bdkrb2tm1Jfh and MGI:3710159/MGI:3710159 mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:121339
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6J
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intergenic deletion, Intragenic deletion
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Del(12Bdkrb2-Bdkrb1)1Mki involves 2 genes/genome features (Bdkrb2, Bdkrb1)
View all
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Mutation details: A targeting vector was designed to replace bradykinin receptor, beta 2 exon 3 and the bradykinin receptor, beta 1 exon with a floxed neomycin resistance cassette.
(J:121339)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Carrying any Del(12Bdkrb2-Bdkrb1)1Mki Mutation: |
1 strain or line available
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Original: |
J:121339 Kakoki M, et al., Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7576-81 |
All: |
5 reference(s) |
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