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Bdkrb2/Bdkrb1tm1Mki
Targeted Allele Detail
Nomenclature
Symbol: Bdkrb2/Bdkrb1tm1Mki
Name: bradykinin receptor, beta 2; targeted mutation 1, Masao Kakoki
MGI ID: MGI:3710158
Synonyms: B1RB2R-null, Bdkrb1-/Bdkrb2-
Gene: Bdkrb2  Location: Chr12:105563172-105593071 bp, + strand  Genetic Position: Chr12, 55.76 cM
Histological changes in the postischemic kidneys of wild type, Bdkrb2tm1Jfh/Bdkrb2tm1Jfh and Bdkrb2/Bdkrb1tm1Mki/Bdkrb2/Bdkrb1tm1Mki mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121339
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
 
Mutation details
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bdkrb2 Mutation:  7 strains or lines available
References
Original:  J:121339 Kakoki M, et al., Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7576-81
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory