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Targeted Allele Detail
Symbol: Gt(ROSA)26Sortm2(SS18)Mrc
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Mario R Capecchi
MGI ID: MGI:3710095
Synonyms: SSM1
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:120967
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
Gt(ROSA)26Sortm2(SS18)Mrc expresses 1 gene
Mutation detailsA targeting vector was designed to insert human synovial sarcoma translocation, chromosome 18, (SS18) into the locus. The vector also contained a strong transcriptional termination signal, NeoPA, flanked by loxP sites, such that the inserted cDNA is not transcribed without the presence of cre recombinase. (J:120967)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  290 strains or lines available
Original:  J:120967 Haldar M, et al., A conditional mouse model of synovial sarcoma: insights into a myogenic origin. Cancer Cell. 2007 Apr;11(4):375-88
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.0
The Jackson Laboratory