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Ghrltm1Mko
Targeted Allele Detail
Nomenclature
Symbol: Ghrltm1Mko
Name: ghrelin; targeted mutation 1, Masayasu Kojima
MGI ID: MGI:3709886
Gene: Ghrl  Location: Chr6:113716119-113719880 bp, - strand  Genetic Position: Chr6, 52.84 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121019
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    The entire sequence has been deleted. Northern blot confirmed absence of transcript. (J:121019)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ghrl Mutation:  3 strains or lines available
References
Original:  J:121019 Dezaki K, et al., Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance. Diabetes. 2006 Dec;55(12):3486-93
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory