Mir155^tm1Brd
Targeted Allele Detail

Summary

• Symbol: Mir155^tm1Brd
• Name: microRNA 155; targeted mutation 1, Allan Bradley
• MGI ID: MGI:3709880
• Synonyms: bic^Brd-m1, bic^m1
• Gene: Mir155 Location: Chr16:84511028-84511092 bp, + strand Genetic Position: Chr16, 46.92 cM
• Alliance: Mir155^tm1Brd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121095
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• A floxed neo was inserted to replace the hairpin precursor within exon 2 of the locus. (J:121095)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir155 Mutation: 11 strains or lines available

References

• Original: J:121095 Rodriguez A, et al., Requirement of bic/microRNA-155 for normal immune function. Science. 2007 Apr 27;316(5824):608-11
• All: 2 reference(s)