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Tg(Pax8-rtTA2S*M2)1Koes
Transgene Detail
Nomenclature
Symbol: Tg(Pax8-rtTA2S*M2)1Koes
Name: transgene insertion 1, Robert Koesters
MGI ID: MGI:3709326
Synonyms: Pax8-rtTA
Transgene: Tg(Pax8-rtTA2S*M2)1Koes  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F2
Transgene
description
Transgene Type:    Transgenic (random, expressed)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Notes
Phenotypic Similarity to Human Syndrome: adult onset polycystic kidney disease in mice hemizygous for Tg(Pax8-rtTA2S*M2)1Koes and Tg(tetO-MYC)36aBop (J:1409250)

References
Original:  J:140925 Traykova-Brauch M, et al., An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice. Nat Med. 2008 Sep;14(9):979-84
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory