About   Help   FAQ
Pdcd4tm1Yhcn
Targeted Allele Detail
Summary
Symbol: Pdcd4tm1Yhcn
Name: programmed cell death 4; targeted mutation 1, Youhai H Chen
MGI ID: MGI:3707444
Synonyms: Pdcd4-
Gene: Pdcd4  Location: Chr19:53880662-53918291 bp, + strand  Genetic Position: Chr19, 48.73 cM
Alliance: Pdcd4tm1Yhcn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:120583
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exons 3 and 4 with a neomycin resistance cassette. Absence of protein was confirmed in mutant lymphoid organs. (J:120583)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdcd4 Mutation:  20 strains or lines available
References
Original:  J:120583 Hilliard A, et al., Translational regulation of autoimmune inflammation and lymphoma genesis by programmed cell death 4. J Immunol. 2006 Dec 1;177(11):8095-102
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory