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Deddtm1Tmiy
Targeted Allele Detail
Nomenclature
Symbol: Deddtm1Tmiy
Name: death effector domain-containing; targeted mutation 1, Toru Miyazaki
MGI ID: MGI:3707325
Synonyms: Dedd-
Gene: Dedd  Location: Chr1:171329145-171342331 bp, + strand  Genetic Position: Chr1, 79.34 cM, cytoband H2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119734
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exons 1 and 2 with a neomycin resistance cassette. Northern blot confirmed absence of transcription in mutants. (J:119734)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dedd Mutation:  19 strains or lines available
References
Original:  J:119734 Arai S, et al., Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2289-94
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory