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DbnlGt(betageo)11Byg
Gene trapped Allele Detail
Summary
Symbol: DbnlGt(betageo)11Byg
Name: drebrin-like; gene trap 11, BayGenomics
MGI ID: MGI:3706950
Synonyms: Abp1-
Gene: Dbnl  Location: Chr11:5738488-5750962 bp, + strand  Genetic Position: Chr11, 3.87 cM
Alliance: DbnlGt(betageo)11Byg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119847
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsA gene trap vector containing a betageo-IRES-PLAP-pA was inserted into intron 8 of the locus. A fusion protein consisting of exons 1-8 and the beta-geo was detected at low levels, and Western blot confirmed absence of wild-type protein in spleen and thymus. (J:119847)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dbnl Mutation:  27 strains or lines available
References
Original:  J:119847 Han J, et al., HIP-55 is important for T-cell proliferation, cytokine production, and immune responses. Mol Cell Biol. 2005 Aug;25(16):6869-78
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory