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Abca3tm1Frm
Targeted Allele Detail
Nomenclature
Symbol: Abca3tm1Frm
Name: ATP-binding cassette, sub-family A (ABC1), member 3; targeted mutation 1, Mason W Freeman
MGI ID: MGI:3706347
Gene: Abca3  Location: Chr17:24351950-24410201 bp, + strand  Genetic Position: Chr17, 12.38 cM, cytoband A3.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:120296
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abca3 Mutation:  5 strains or lines available
References
Original:  J:120296 Fitzgerald ML, et al., ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol. J Lipid Res. 2007 Mar;48(3):621-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory