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Rictortm1.3Mgn
Targeted Allele Detail
Nomenclature
Symbol: Rictortm1.3Mgn
Name: RPTOR independent companion of MTOR, complex 2; targeted mutation 1.3, Mark A Magnuson
MGI ID: MGI:3703325
Synonyms: riclacZ
Gene: Rictor  Location: Chr15:6708379-6800401 bp, + strand  Genetic Position: Chr15, 3.25 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119564
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsUpon expression of cre recombinase in the germline, exon 3 was removed from the locus, leaving an frt-flanked lacZ-pA cassette. Absence of protein was confirmed by Western blot analysis. (J:119564)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rictor Mutation:  17 strains or lines available
References
Original:  J:119564 Shiota C, et al., Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev Cell. 2006 Oct;11(4):583-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory