Ticam1^tm1Tsse
Targeted Allele Detail

Summary

• Symbol: Ticam1^tm1Tsse
• Name: TIR domain containing adaptor molecule 1; targeted mutation 1, Tsukasa Seya
• MGI ID: MGI:3701472
• Gene: Ticam1 Location: Chr17:56576462-56583767 bp, - strand Genetic Position: Chr17, 29.24 cM
• Alliance: Ticam1^tm1Tsse page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118750
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced by a pgk-b-neo cassette. (J:118750)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ticam1 Mutation: 53 strains or lines available

References

• Original: J:118750 Akazawa T, et al., Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):252-7
• All: 16 reference(s)