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Adgre5tm1Kake
Targeted Allele Detail
Nomenclature
Symbol: Adgre5tm1Kake
Name: adhesion G protein-coupled receptor E5; targeted mutation 1, Kathleen Kelly
MGI ID: MGI:3700734
Gene: Adgre5  Location: Chr8:83723251-83741326 bp, - strand  Genetic Position: Chr8, 40.22 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118705
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details11.8Kb of the genomic sequence containing exons 2 through 12 was replaced with a PGKneo cassette. Absence of expression was confirmed by CD97-antibody staining in hematopoietic cells from homozygous mice. (J:118705)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adgre5 Mutation:  57 strains or lines available
References
Original:  J:118705 Wang T, et al., Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97. Infect Immun. 2007 Mar;75(3):1144-53
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory