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Tg(Cdh5-cre/ERT2)CIVE23Mlia
Transgene Detail
Nomenclature
Symbol: Tg(Cdh5-cre/ERT2)CIVE23Mlia
Name: transgene insertion CIVE23, M Luisa Iruela-Arispe
MGI ID: MGI:3700149
Synonyms: 236849, Tg(Cdh5-cre)CIVE23Mlia, VECad-Cre-ERT2, VE-Cadherin-CreERT2, VE-CadheriniCre
Transgene: Tg(Cdh5-cre/ERT2)CIVE23Mlia  Location: unknown  Genetic Position: Chr3, Syntenic
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Duplication, Insertion
 
Mutation detailsThe Cre-ERT2 expression cassette was placed under the regulatory control of the mouse cadherin 5 promoter. 8 lines were obtained. Line CIVE23 inserted 138 kb upstream of Ankrd50 (chr3:38,522,028; NCBI37/mm9) with a fragment of Vat1l and a 87.6 kb genomic duplication occured at the integration site. (J:116638, J:240920)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdh5     Summary of all recombinase alleles driven by Cdh5. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:116638 Monvoisin A, et al., VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium. Dev Dyn. 2006 Dec;235(12):3413-22
All:  40 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory