About   Help   FAQ
Ptpn13tm1Gru
Targeted Allele Detail
Nomenclature
Symbol: Ptpn13tm1Gru
Name: protein tyrosine phosphatase, non-receptor type 13; targeted mutation 1, Michael J Grusby
MGI ID: MGI:3700029
Gene: Ptpn13  Location: Chr5:103425192-103598303 bp, + strand  Genetic Position: Chr5, 50.43 cM, cytoband E-F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118426
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin resistance cassette was inserted to disrupt the exon encoding amino acids 452-526. Northern blot confirmed absence of transcript in mutants. (J:118426)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptpn13 Mutation:  59 strains or lines available
References
Original:  J:118426 Nakahira M, et al., Regulation of Signal Transducer and Activator of Transcription Signaling by the Tyrosine Phosphatase PTP-BL. Immunity. 2007 Feb;26(2):163-76
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory