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Targeted Allele Detail
Symbol: Ptpn13tm1Gru
Name: protein tyrosine phosphatase, non-receptor type 13; targeted mutation 1, Michael J Grusby
MGI ID: MGI:3700029
Gene: Ptpn13  Location: Chr5:103425192-103598303 bp, + strand  Genetic Position: Chr5, 50.43 cM, cytoband E-F
Germline Transmission:  Earliest citation of germline transmission: J:118426
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsA neomycin resistance cassette was inserted to disrupt the exon encoding amino acids 452-526. Northern blot confirmed absence of transcript in mutants. (J:118426)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptpn13 Mutation:  59 strains or lines available
Original:  J:118426 Nakahira M, et al., Regulation of Signal Transducer and Activator of Transcription Signaling by the Tyrosine Phosphatase PTP-BL. Immunity. 2007 Feb;26(2):163-76
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
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