Bmp2^tm1Cjt
Targeted Allele Detail

Summary

• Symbol: Bmp2^tm1Cjt
• Name: bone morphogenetic protein 2; targeted mutation 1, Clifford J Tabin
• MGI ID: MGI:3699309
• Synonyms: Bmp2^c
• Gene: Bmp2 Location: Chr2:133394079-133404805 bp, + strand Genetic Position: Chr2, 65.21 cM
• Alliance: Bmp2^tm1Cjt page

Mice deficient singly or in various combinations of Bmp2, Bmp4 and Bmp7 display limb defects

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118257
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was flanked with loxP sites. (J:118257)

Expression

In Mice Carrying this Mutation:	64 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp2 Mutation: 26 strains or lines available

References

• Original: J:118257 Bandyopadhyay A, et al., Genetic Analysis of the Roles of BMP2, BMP4, and BMP7 in Limb Patterning and Skeletogenesis. PLoS Genet. 2006 Dec 22;2(12):e216
• All: 11 reference(s)