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Dlg1tm1Jhm
Targeted Allele Detail
Nomenclature
Symbol: Dlg1tm1Jhm
Name: discs, large homolog 1 (Drosophila); targeted mutation 1, Jeffrey H Miner
MGI ID: MGI:3699270
Synonyms: Dlgh1-
Gene: Dlg1  Location: Chr16:31663443-31873350 bp, + strand  Genetic Position: Chr16, 22.4 cM
Dlg1tm1Jhm/Dlg1tm1Jhm embryos exhibit urinary tract abnormalities, including hydroephrosis

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118250
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129 x C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 4 was replaced by a neomycin resistance cassette. (J:118250)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dlg1 Mutation:  42 strains or lines available
Notes
ES cell line = F1BS
References
Original:  J:118250 Mahoney ZX, et al., Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19872-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory