Sall4^tm2Ryn
Targeted Allele Detail

Summary

• Symbol: Sall4^tm2Ryn
• Name: spalt like transcription factor 4; targeted mutation 2, Ryuichi Nishinakamura
• MGI ID: MGI:3699176
• Synonyms: Sall4-Betageo
• Gene: Sall4 Location: Chr2:168590252-168609121 bp, - strand Genetic Position: Chr2, 88.99 cM
• Alliance: Sall4^tm2Ryn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118119
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exons 2 and 3 and intron 2 are replaced with and IRES-beta-geo cassette. (J:118119)

Expression

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall4 Mutation: 144 strains or lines available

References

• Original: J:118119 Sakaki-Yumoto M, et al., The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Development. 2006 Aug;133(15):3005-13
• All: 1 reference(s)