Dmrta1^tm1.1Zark
Targeted Allele Detail

Summary

• Symbol: Dmrta1^tm1.1Zark
• Name: doublesex and mab-3 related transcription factor like family A1; targeted mutation 1.1, David Zarkower
• MGI ID: MGI:3699123
• Synonyms: Dmrt4^delta
• Gene: Dmrta1 Location: Chr4:89576435-89583003 bp, + strand Genetic Position: Chr4, 42.15 cM
• Alliance: Dmrta1^tm1.1Zark page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118110
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 1 was removed by cre mediated recombination. RT-PCR confirmed absence of the major DM domain-encoding mRNA. (J:118110)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmrta1 Mutation: 25 strains or lines available

References

• Original: J:118110 Balciuniene J, et al., Mice mutant in the DM domain gene Dmrt4 are viable and fertile but have polyovular follicles. Mol Cell Biol. 2006 Dec;26(23):8984-91
• All: 1 reference(s)