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Thoc1tm2.1Dwg
Targeted Allele Detail
Summary
Symbol: Thoc1tm2.1Dwg
Name: THO complex 1; targeted mutation 2.1, David W Goodrich
MGI ID: MGI:3698314
Gene: Thoc1  Location: Chr18:9958176-9995486 bp, + strand  Genetic Position: Chr18, 4.91 cM
Alliance: Thoc1tm2.1Dwg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117869
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT site flanked neomycin selection cassette was inserted into intron 5. LoxP sites were inserted into intron 5, upstream of the first FRT site, and intron 7. The neo cassette was removed through Flp-mediated recombination. Exons 6-7 remain flanked by loxP sites. (J:117869)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thoc1 Mutation:  45 strains or lines available
References
Original:  J:117869 Wang X, et al., An allelic series for studying the mouse Thoc1 gene. Genesis. 2007 Jan;45(1):32-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory