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Zic3tm1Jwb
Targeted Allele Detail
Nomenclature
Symbol: Zic3tm1Jwb
Name: zinc finger protein of the cerebellum 3; targeted mutation 1, John W Belmont
MGI ID: MGI:3698161
Synonyms: Zic3neo, Zic3null
Gene: Zic3  Location: ChrX:58022700-58041736 bp, + strand  Genetic Position: ChrX, 32.56 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117748
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsAn frt-flanked neomycin resistance cassette was inserted in antisense orientation upstream of the locus. (J:117748)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 15 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zic3 Mutation:  38 strains or lines available
References
Original:  J:117748 Zhu L, et al., Craniofacial, skeletal, and cardiac defects associated with altered embryonic murine Zic3 expression following targeted insertion of a PGK-NEO cassette. Front Biosci. 2007;12:1680-90
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory