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Spasttm1.1Jme
Targeted Allele Detail
Nomenclature
Symbol: Spasttm1.1Jme
Name: spastin; targeted mutation 1.1, Judith Melki
MGI ID: MGI:3698038
Synonyms: Spdelta
Gene: Spast  Location: Chr17:74338987-74391115 bp, + strand  Genetic Position: Chr17, 45.64 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117740
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exons 5-7 were removed via cre-mediated excision. (J:117740)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spast Mutation:  15 strains or lines available
References
Original:  J:117740 Tarrade A, et al., A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition. Hum Mol Genet. 2006 Dec 15;15(24):3544-58
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory