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Targeted Allele Detail
Symbol: Ppp4ctm1Tht
Name: protein phosphatase 4, catalytic subunit; targeted mutation 1, Tse-Hua Tan
MGI ID: MGI:3697685
Synonyms: PP4flox
Gene: Ppp4c  Location: Chr7:126785866-126792496 bp, - strand  Genetic Position: Chr7, 69.25 cM
Germline Transmission:  Earliest citation of germline transmission: J:117684
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsLoxP sites were inserted to flank exon 3. A neo included in the vector was subsequently removed via FLP mediated recombination. (J:117684)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppp4c Mutation:  15 strains or lines available
Original:  J:117684 Shui JW, et al., Conditional knockout mice reveal an essential role of protein phosphatase 4 in thymocyte development and pre-T-cell receptor signaling. Mol Cell Biol. 2007 Jan;27(1):79-91
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory