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Sox13tm1Jskg
Targeted Allele Detail
Nomenclature
Symbol: Sox13tm1Jskg
Name: SRY (sex determining region Y)-box 13; targeted mutation 1, Joonsoo Kang
MGI ID: MGI:3697320
Synonyms: Sox13-
Gene: Sox13  Location: Chr1:133382303-133424377 bp, - strand  Genetic Position: Chr1, 57.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117301
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA floxed neo was inserted into intron 3 and an additional loxP site was inserted into intron 11. A ~500 bp deletion was created in intron 5 for ES cell screening purposes. Transient cre expression resulted in the deletion of exons 4-11. Semi-quantitative RT-PCR confirmed lack of expression in mutant thymus. (J:117301)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox13 Mutation:  48 strains or lines available
References
Original:  J:117301 Melichar HJ, et al., Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13. Science. 2007 Jan 12;315(5809):230-3
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory