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Casp8tm1Hed
Targeted Allele Detail
Nomenclature
Symbol: Casp8tm1Hed
Name: caspase 8; targeted mutation 1, Stephen M Hedrick
MGI ID: MGI:3696985
Synonyms: Casp8fl
Gene: Casp8  Location: Chr1:58795374-58847503 bp, + strand  Genetic Position: Chr1, 29.19 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116713
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 3 was flanked with loxP sites by homologous recombination. (J:116713)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Casp8 Mutation:  4 strains or lines available
References
Original:  J:116713 Beisner DR, et al., Cutting edge: innate immunity conferred by B cells is regulated by caspase-8. J Immunol. 2005 Sep 15;175(6):3469-73
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory