About   Help   FAQ
Pde3btm1Yhc
Targeted Allele Detail
Nomenclature
Symbol: Pde3btm1Yhc
Name: phosphodiesterase 3B, cGMP-inhibited; targeted mutation 1, Young Hun Choi
MGI ID: MGI:3696665
Synonyms: Pde3b-
Gene: Pde3b  Location: Chr7:114415222-114537938 bp, + strand  Genetic Position: Chr7, 59.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117353
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace a 600 bp part of exon 1, including the ATG, with a neomycin resistance cassette. (J:117353)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pde3b Mutation:  3 strains or lines available
References
Original:  J:117353 Choi YH, et al., Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice. J Clin Invest. 2006 Dec;116(12):3240-51
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory