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Clec7atm1Gdb
Targeted Allele Detail
Nomenclature
Symbol: Clec7atm1Gdb
Name: C-type lectin domain family 7, member a; targeted mutation 1, Gordon D Brown
MGI ID: MGI:3695710
Synonyms: Clec7a-, dectin-1-
Gene: Clec7a  Location: Chr6:129438554-129449742 bp, - strand  Genetic Position: Chr6, 63.34 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116669
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 1-3 were replaced with a neomycin resistance gene. (J:116669)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clec7a Mutation:  15 strains or lines available
References
Original:  J:116669 Taylor PR, et al., Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol. 2007 Jan;8(1):31-8
All:  69 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory