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Scn11atm1Wlf
Targeted Allele Detail
Nomenclature
Symbol: Scn11atm1Wlf
Name: sodium channel, voltage-gated, type XI, alpha; targeted mutation 1, Clifford J Woolf
MGI ID: MGI:3695487
Synonyms: Nav1.9-
Gene: Scn11a  Location: Chr9:119753763-119825456 bp, - strand  Genetic Position: Chr9, 71.33 cM, cytoband F3-F4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116768
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn IRES-lacZ cassette with a loxP-flanked neo was inserted into the locus in exon 4, replacing most of exon 4 and all of exons 5 and 6. (J:116768)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scn11a Mutation:  35 strains or lines available
References
Original:  J:116768 Amaya F, et al., The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. J Neurosci. 2006 Dec 13;26(50):12852-60
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory