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Ndfip1Gt(RRD002)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: Ndfip1Gt(RRD002)Byg
Name: Nedd4 family interacting protein 1; gene trap RRD002, BayGenomics
MGI ID: MGI:3695433
Synonyms: Ndfip1-
Gene: Ndfip1  Location: Chr18:38418907-38465197 bp, + strand  Genetic Position: Chr18, 20.32 cM, cytoband B3
Mutation
origin
Mutant Cell Line:  RRD002
Germline Transmission:  Earliest citation of germline transmission: J:116617
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation detailsA gene trap vector was inserted into intron 2, resulting in the truncation of the transcript just beyond exon 2. (J:116617)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ndfip1 Mutation:  6 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:116617 Oliver PM, et al., Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 2006 Dec;25(6):929-40
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory