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Trdmt1tm1Bes
Targeted Allele Detail
Nomenclature
Symbol: Trdmt1tm1Bes
Name: tRNA aspartic acid methyltransferase 1; targeted mutation 1, Timothy H Bestor
MGI ID: MGI:3695409
Synonyms: Dnmt2-
Gene: Trdmt1  Location: Chr2:13513825-13549479 bp, - strand  Genetic Position: Chr2, 10.0 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104615
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsLoxP sites were introduced to flank exons 7-10 of the gene. Cre-mediated recombination resulted in deletion of exons 7-10.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trdmt1 Mutation:  34 strains or lines available
References
Original:  J:104615 Goll MG, et al., Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science. 2006 Jan 20;311(5759):395-8
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory