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Nox1tm1Cyn
Targeted Allele Detail
Nomenclature
Symbol: Nox1tm1Cyn
Name: NADPH oxidase 1; targeted mutation 1, Chihiro Yabe-Nishimura
MGI ID: MGI:3695407
Gene: Nox1  Location: ChrX:134086421-134221956 bp, - strand  Genetic Position: ChrX, 55.69 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116837
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3-6 were replaced with a neomycin resistance gene. Transcripts were not detected in mutants by RT-PCR analysis. (J:116837)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nox1 Mutation:  4 strains or lines available
References
Original:  J:116837 Matsuno K, et al., Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation. 2005 Oct 25;112(17):2677-85
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory