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Slc17a6tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Slc17a6tm1Lex
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3693887
Synonyms: Vglut2-
Gene: Slc17a6  Location: Chr7:51622006-51671119 bp, + strand  Genetic Position: Chr7, 32.78 cM, cytoband B4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116159
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    An IRES-betageo-PGKpuro replaced exon 2, resulting in the disruption of the reading frame. (J:116159)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 9 assay results
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc17a6 Mutation:  42 strains or lines available
References
Original:  J:116159 Moechars D, et al., Vesicular glutamate transporter VGLUT2 expression levels control quantal size and neuropathic pain. J Neurosci. 2006 Nov 15;26(46):12055-66
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory