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Sytl2tm1Mitf
Targeted Allele Detail
Nomenclature
Symbol: Sytl2tm1Mitf
Name: synaptotagmin-like 2; targeted mutation 1, Mitsunori Fukuda
MGI ID: MGI:3693881
Synonyms: Slp2-a-
Gene: Sytl2  Location: Chr7:90302252-90410719 bp, + strand  Genetic Position: Chr7, 50.54 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116278
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced the entire protein-coding region in exon 1. Western blot confirmed absence of protein in mutant stomachs. (J:116278)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sytl2 Mutation:  36 strains or lines available
References
Original:  J:116278 Saegusa C, et al., Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells. Genes Cells. 2006 Jun;11(6):623-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory