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Six3tm2.1Gco
Targeted Allele Detail
Nomenclature
Symbol: Six3tm2.1Gco
Name: sine oculis-related homeobox 3; targeted mutation 2.1, Guillermo Oliver
MGI ID: MGI:3693322
Synonyms: Six3delta
Gene: Six3  Location: Chr17:85613608-85629302 bp, + strand  Genetic Position: Chr17, 55.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116102
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 1 was removed via cre mediated recombination. (J:116102)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 8 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Six3 Mutation:  5 strains or lines available
References
Original:  J:116102 Liu W, et al., Six3 activation of Pax6 expression is essential for mammalian lens induction and specification. EMBO J. 2006 Nov 15;25(22):5383-95
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory