About   Help   FAQ
Agertm1.1Hyam
Targeted Allele Detail
Nomenclature
Symbol: Agertm1.1Hyam
Name: advanced glycosylation end product-specific receptor; targeted mutation 1.1, Hiroshi Yamamoto
MGI ID: MGI:3692766
Synonyms: Rage-
Gene: Ager  Location: Chr17:34597862-34600936 bp, + strand  Genetic Position: Chr17, 18.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116040
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 1 and 2 were removed via transient cre-mediated recombination. Western blot of mutant lung and kidney confirm absence of protein in mutants. (J:116040)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ager Mutation:  11 strains or lines available
References
Original:  J:116040 Myint KM, et al., RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin. Diabetes. 2006 Sep;55(9):2510-22
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/12/2018
MGI 6.12
The Jackson Laboratory