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Tg(Sim1-cre)1Lowl
Transgene Detail
Nomenclature
Symbol: Tg(Sim1-cre)1Lowl
Name: transgene insertion 1, Bradford B Lowell
MGI ID: MGI:3692526
Synonyms: Sim1Cre, Sim1-Cre
Transgene: Tg(Sim1-cre)1Lowl  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe cre ATG was inserted via recombineering techniques, into the Sim1 ATG site of a BAC containing 137.1 kb of genomic C57BL/6 Sim1 sequences up to and including exon 8. The inserted cre sequence deleted the first 31 bp of the Sim1 gene. (J:115192)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sim1     Summary of all recombinase alleles driven by Sim1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 35 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:115192 Balthasar N, et al., Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell. 2005 Nov 4;123(3):493-505
All:  32 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/20/2020
MGI 6.16
The Jackson Laboratory