About   Help   FAQ
Map3k12tm1Shir
Targeted Allele Detail
Nomenclature
Symbol: Map3k12tm1Shir
Name: mitogen-activated protein kinase kinase kinase 12; targeted mutation 1, Syu-ichi Hirai
MGI ID: MGI:3692456
Synonyms: Dlk-
Gene: Map3k12  Location: Chr15:102497649-102517064 bp, - strand  Genetic Position: Chr15, 57.63 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:115575
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1, 2 and part of exon 3 were replaced by lacZ. No protein was detected in mutant brains by immunoprecipitation and Western blotting. (J:115575)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Map3k12 Mutation:  28 strains or lines available
References
Original:  J:115575 Hirai S, et al., The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex. J Neurosci. 2006 Nov 15;26(46):11992-2002
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/12/2017
MGI 6.10
The Jackson Laboratory