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Targeted Allele Detail
Symbol: Map3k12tm1Shir
Name: mitogen-activated protein kinase kinase kinase 12; targeted mutation 1, Syu-ichi Hirai
MGI ID: MGI:3692456
Synonyms: Dlk-
Gene: Map3k12  Location: Chr15:102497649-102517064 bp, - strand  Genetic Position: Chr15, 57.63 cM, cytoband F3
Germline Transmission:  Earliest citation of germline transmission: J:115575
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 1, 2 and part of exon 3 were replaced by lacZ. No protein was detected in mutant brains by immunoprecipitation and Western blotting. (J:115575)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Map3k12 Mutation:  29 strains or lines available
Original:  J:115575 Hirai S, et al., The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex. J Neurosci. 2006 Nov 15;26(46):11992-2002
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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