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Targeted Allele Detail
Symbol: Sall4tm1Tre
Name: spalt like transcription factor 4; targeted mutation 1, Mathias Treier
MGI ID: MGI:3692447
Synonyms: Sall4H2bEGFP
Gene: Sall4  Location: Chr2:168748332-168767943 bp, - strand  Genetic Position: Chr2, 88.99 cM
Germline Transmission:  Earliest citation of germline transmission: J:115635
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to replace exon 2, encompassing the sequence for the glutamine repeat as well as the first six zinc finger motifs, with an IRES-Histone2bEGFP cassette. The resulting protein was truncated after amino acid 58. A floxed neo in the vector was removed by cre-mediated recombination. (J:115635)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sall4 Mutation:  133 strains or lines available
Original:  J:115635 Elling U, et al., Murine inner cell mass-derived lineages depend on Sall4 function. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16319-24
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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