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Six2tm1Gco
Targeted Allele Detail
Nomenclature
Symbol: Six2tm1Gco
Name: sine oculis-related homeobox 2; targeted mutation 1, Guillermo Oliver
MGI ID: MGI:3691857
Synonyms: Six2-
Gene: Six2  Location: Chr17:85684277-85688274 bp, - strand  Genetic Position: Chr17, 55.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:115344
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a PGK-neo cassette. Exon 1 contains the transcriptional initiation site, the Six domain and the homeodomain. (J:115344)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Six2 Mutation:  6 strains or lines available
References
Original:  J:115344 Self M, et al., Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney. EMBO J. 2006 Nov 1;25(21):5214-28
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory